“I have used DDR for a number of supply chain projects over the past 5 years and believe that they continually deliver significant value and strong customer service. The DDR team does a nice job up front, working with the customer to define the project deliverables and to ensure alignment on scope. Then they deliver.”
John Condon
SVP Pharmaceutical
Operations
Vertex Pharmaceuticals, Inc
![Manufacturing Supply Chain](../jpg/manuf.jpg)
Manufacturing Supply Chain
Through proven planning and analytical methodology, strategic outsourcing expertise, and a bottom-up understanding of how manufacturing and supply chains work, DDR develops and executes individualized solutions that keep materials off the critical path – ensuring that each therapeutic product is always available when and where it is needed.
Past projects have included:
- Project Management
- CMO Selection, Management and Oversight
- Vendor Selection, Management and Oversight
- Process Development
- Technology Transfer
- On-site Representation (Person in Plant)
- Process and Manufacturing Yield and Throughput optimization
- Plant Management
- Clinical Trial Supply Strategies and Chain Management
- Commercial Launch Planning
- Commercial Supply Strategies and Management
- Product Label Development
- Global Distribution Management
- Selection and Integration with Inventory Management Systems
Case Study 1: Small Molecule Oncology Product
Initial Client Contact: Multiple near stock outs in pivotal Phase 2 – DDR retained to determine cause and provide solution
- Designed Supply Chain
- Managed Clinical and Commercial Supply Operations
- Optimized batch size
- Optimized product presentation
- Selected Manufacturing, Packaging, 3PL
- Managed Technology Transfer
- Developed Planning Process
- Developed Job Descriptions – Hired and Trained Staff
Quantitative Impacts: Clinical trials successfully completed. Product launched.
Case Study 2: Peptide Thrombolytic Product
Initial Client Contact: Supply Chain Manager quit abruptly
- Managed Clinical and Commercial Supply Operations
- Optimized Batch Size
- Developed Planning Process
- Developed Job Descriptions – Hire and Train Staff
Quantitative Impacts: 8% reduction in COGS and 17% decrease in drug substance requirement for this capacity-constrained product.
Case Study 3: Vaccine Product
Initial Client Contact: Poor results endangered ability to hit government contractual commitments
- Managed Commercial Manufacturing Operations
- Developed Planning Process
- Implemented Vendor Performance Management Process
- Selected, implemented, and validated ERP
- Developed job descriptions, hired and trained employees
Quantitative Impacts: Contractual commitments fulfilled. 20% increase in yield.